PediFETCh: Fecal Transplant in Paediatric Ulcerative Colitis

McMaster Paediatric FMT Research Collaboration

 *Study recruitment complete

Results of the First Pilot Randomized Controlled Trial of Fecal Microbiota Transplant In Pediatric Ulcerative Colitis: Lessons, Limitations, and Future Prospects. Gastroenterology. Published Ahead of Print. 2021

<https://www.gastrojournal.org/article/S0016-5085(21)00739-3/>

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Children with ulcerative colitis have unique bacteria in their intestines that differs from children who are healthy, which may be a contributing factor in IBD.

In the “PediFETCh” study (Pediatric Fecal Microbiota Transplant for Ulcerative Colitis) – the first and only of its kind in Canada – our team is testing whether the transplantation of healthy fecal matter from a donor can improve symptoms in kids with IBD. It’s something that’s already been shown to be effective in adults.

This study will tell us whether fecal transplants can be a viable treatment for kids with ulcerative colitis who can’t manage the disease with their current medications.